Abstract #4442

MEG-Guided Surface Coil Imaging at 3 Tesla in Patients with Refractory Epilepsy: Preliminary Results

Samuel Lapere¹, Evelien Carrette², Paul Boon², Kristl Vonck², Xavier De Tige³, Eric Achten¹, Karel Deblaere¹

¹Department of Radiology, Ghent University Hospital, Ghent, Belgium; ²Reference Center for Refractory Epilepsy, Department of Neurology, Ghent University Hospital; ³Laboratoire de Cartographie Fonctionelle du Cerveau, ULB Erasmus Hospital Brussels, Belgium

Patients with refractory epilepsy in whom the epileptogenic zone cannot be precisely identified are not likely to undergo resective surgery. This study aims to assess the potential of surface coil imaging at 3T guided by magnetoencephalography (MEG) to locate the epileptogenic zone. Fifteen patients with dipole clustering on MEG (indicating the possible epileptogenic zone) were scanned with a surface coil at 3T. MEG-guided surface coil imaging at 3T showed an added value in the detection of lesions previously not visible or missed on 3T MRI, and demonstrated an improved delineation and electrophysiological validation of previously known lesions.