Charlotte Rosso1,2, Yohan Attal2,
Sandrine Deltour1, Nidiyare Hevia-Montiel2, Eric
Bardinet2,3, Dider Dormont2,4, Stephane Lehericy2,4,
Sylvain Baillet2, Yves Samson1,5
1Urgences Cerebro-Vasculaires,
Pitie-Salpetriere Hospital, Paris, France; 2CRICM, INSERM UMR S_975,
CNRS UMR_7725, Equipe COGIMAGE, Pitie-Salpetriere Hospital, Paris, France; 3Centre
for NeuroImaging Research CENIR, Pitie-Salpetriere Hospital, Paris, France;
4Neuroradiology Department, Pitie-Salpetriere Hospital, Paris,
France; 5CRICM, INSERM UMR S_975, CNRS UMR_7725, Equipe COGIMAGE,
Pitie-Salpetriere, Paris, France
In
this work, we used ADC maps to predict infarct growth. The method is based on
an algorithm able to make the initial infarct lesion growing up, taking in
account the slight ADC decrease which occurs in the at-risk tissue. Patients
(n=216) with MCA acute stroke confirmed by an initial (<6H) and a control
MRI have been tested. Predicted vs. final infarct sizes and growths were
significantly correlated. The accuracy to predict infarct growth status
(patients with or without infarct growth) reached 76 %. The ADC-defined
tissue-at-risk is a hallmark of the penumbra since MCA recanalization could
spare it.