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Abstract #4167

Long Term Evaluation of the 1.28 Ppm After Transplantation of Purified Neural Progenitor Cells in the Brain

Chiao-Chi V. Chen1, Kuan-Chi Mo1, Ching-Yu Chuang2, Hung-Chih Kuo3, Chen Chang1

1Functional and Micro-magnetic Resonance Imaging Center, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; 2Institute of Biotechnology, National Taiwan University, Taipei, Taiwan; 3Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan


The present study aimed to use in vivo MRS to track the long term changes and consequences of purified neural progenitor cells (NPCs) in the brain. Following transplantation, there were signal intensity changes over time at the 1.28 ppm along with the NAA signal, which may represent the variations of the functional status of the NPC biomarker.