Chiao-Chi V. Chen1, Kuan-Chi Mo1,
Ching-Yu Chuang2, Hung-Chih Kuo3, Chen Chang1
1Functional and Micro-magnetic
Resonance Imaging Center, Institute of Biomedical Sciences, Academia Sinica,
Taipei, Taiwan; 2Institute of Biotechnology, National Taiwan
University, Taipei, Taiwan; 3Institute of Cellular and Organismic
Biology, Academia Sinica, Taipei, Taiwan
The
present study aimed to use in vivo MRS to track the long term changes and
consequences of purified neural progenitor cells (NPCs) in the brain.
Following transplantation, there were signal intensity changes over time at
the 1.28 ppm along with the NAA signal, which may represent the variations of
the functional status of the NPC biomarker.