Gerwin P. Schmidt1, Andreas Biffar, Steven
P. Sourbron, Melvin D'Anastasi, Mike Notohamiprodjo, Maximilian F. Reiser,
Andrea Baur-Melnyk
1Department of Radiology, University
Hospitals Munich, Munich, Bavaria, Germany
The
analysis of dynamic contrast-enhanced data provides reproducible quantitative
perfusion parameters in healthy and pathologic bone marrow. Perfusion is
strongly increased in acute osteoporotic fractures yielding areas of
different perfusion parameters, potentially representing different sites of
reactive and reparative process. Furthermore, perfusion parameter changes
correlate with severity of osteoporosis and may serve as a tool to
differentiate various stages of the disease.