Michael H. Buonocore1, David H. Gultekin2,
Michael A. Jacobs3, Steffen Sammet4, Natarajan
Raghunand5, Joshua Levy6, Michael V. Knopp4
1Radiology, UC Davis Imaging Research
Center, Sacramento, CA, United States; 2Memorial Sloan-Kettering
Cancer Center, New York, NY, United States; 3Radiology, Johns
Hopkins University, Baltimore, MD, United States; 4Radiology, Ohio
State University, Columbus, OH, United States; 5Radiology,
University of Arizona, Tucson, AZ, United States; 6The Phantom
Laboratory, Inc., Salem, NY, United States
This
study presents a new DCE-MRI phantom designed for calibration of MRI systems
to be used in multi-site clinical trials. Preliminary results at four
clinical sites show the ability of the phantom to reveal critical
similarities but also expected and unexpected differences in the images and
derived DCE-MRI parameters.