Sung-Hong Park1, Yi Zhang1, Jinqi
Li1, Qi Peng1, Jiongjiong Wang2, Timothy Q.
Duong1
1Research Imaging Institute,
Ophthalmology/Radiology, University of Texas Health Science Center at San
Antonio, San Antonio, TX, United States; 2Radiology and Neurology,
University of Pennsylvania, Philadelphia, PA, United States
Mapping
human retinal blood flow has not been easy with EPI-based arterial spin
labeling (ASL) techniques because of significant susceptibility effects
around eyes. In this study, we propose to use a combination of
pseudo-continuous ASL and balanced steady state free precession (bSSFP)
readout for mapping blood flow in the human retina. The results showed
reproducible human retinal blood flow, free of motion artifacts, image
distortion, signal drop out and bSSFP banding artifacts.