Ciprian Catana1, Andre van der Kouwe1,
Thomas Benner1, Michael Hamm2, Christian J. Michel2,
Matthias Fenchel2, Larry Byars2, Matthias Schmand2,
Alma Gregory Sorensen1
1MGH, Radiology, A.A. Martinos Center
for Biomedical Imaging, Charlestown, MA, United States; 2Siemens
Healthcare
Attenuation
correction is a required step not only for obtaining quantitative data, but
also for performing meaningful qualitative image analysis. In order to
achieve the necessary quantification for accurate quantitative neurological
studies, three main components must be identified: water-based structures,
bone tissue and air-filled cavities.
DUTE sequences can potentially be used for bone/air segmentation. An MR-DUTE-based AC method could in
principle provide accurate estimation of the radiotracer concentration in a
particular voxel. Implementing an
accurate MR-based AC will allow us take advantage of the improved
quantitative capabilities of the combined MR-PET scanner.