Combining EEG and FMRI Data from a Wistar Rat: A New Tool for Comparative Neuroimaging

Akira Sumiyoshi¹, Takeshi Ogawa¹, Ryuta Kawashima¹, Jorge Javier Riera¹

Concurrent recordings of EEG and fMRI are nowadays possible in numerous laboratories for humans. However, its extension to rodents has been limited in terms of the number and the characteristics of the utilized electrodes. Here, we introduce a methodology to obtain EEG recordings from a dense array of scalp electrodes concurrently with fMRI-BOLD in a 7T MRI. We evaluate the performance of the proposed methodology using a conventional forepaw stimulation paradigm in a Wistar rat. By means of the proposed methodology one can have brain electrical source reconstruction in addition to their coupled hemodynamic responses at the level of single voxels.