Chloe Hutton1, Oliver Josephs1,
Jrg Stadler2, Eric Featherstone1, Alphonso Reid1,
Oliver Speck3, Johannes Bernarding4, Nikolaus Weiskopf1
1Wellcome Trust Centre for
Neuroimaging, Institute of Neurology, University College London, London,
United Kingdom; 2Special Lab Non-Invasive Brain Imaging, Leibniz
Institute for Neurobiology, Magdeburg, Germany; 3Department of
Biomedical Magnetic Resonance, Institute for Experimental Physics,
Otto-von-Guericke University, Magdeburg, Germany; 4Institute for
Biometry and Medical Informatics, Faculty of Medicine, Otto-von-Guericke
University, Magdeburg, Germany
This
study aims to demonstrate the impact of physiological noise correction on the
detection of brain activations for BOLD fMRI studies acquired at 7T. We use
fMRI studies of subjects at rest and performing a visual task to estimate
temporal SNR (tSNR) as a function of image SNR and the t-scores associated
with detected activations after performing physiological noise corrections
based on peripheral measurements of subject physiology. The results
demonstrate that the corrections lead to an increase in mean tSNR and
voxel-wise improvements in t-scores in the visual cortex.