ashish gupta1, Abbas Ali Mahdi1,
Kaleem Ahmad1, Kamla Kant Shukla1, S P. Jaiswar2,
S
1Department of Biochemistry, King
Georges Medical University, Lucknow, UP, India; 2Department of
Obstetric & Gynecology, King Georges Medical University, Lucknow, UP,
India; 3Department of Urology, King Georges Medical University,
Lucknow, UP, India
Quantitative
analysis of seminal plasma (n=175) profile was carried out using 1H NMR
spectroscopy and clinical symptoms were also observed in same samples with
standard laboratory method. Multivariate discriminant function analysis (DFA)
was carried out for the NMR observed metabolites and clinical symptoms data
of the infertile and control cases, to find out important signature
descriptors for classification. A new INFERTIX classification model was
developed and proposed which is based on the results obtained from DFA for
the different classes of infertile patients, with very high sensitivity and
specificity values.