Motion-Sensitized Driven-Equilibrium (MSDE) Turbo Spin-Echo Sequence Increases Radiologists' Diagnostic Performance in Detection of Brain Metastasis

Eiki Nagao¹, Takashi Yoshiura¹, Akio Hiwatashi¹, Koji Yamashita¹, Hironori Kamano¹, Yukihisa Takayama¹, Tuvshinjargal Dashjamts¹, Makoto Obara², Tomoyuki Okuaki², Hiroshi Honda¹

Motion-sensitized driven-equilibrium (MSDE) sequence has been reported to effectively suppress signals from flowing blood in vessels that can mimic the brain metastases on post-contrast T1-weighted images. We performed an observer test to determine whether use of a 3D turbo spin-echo (TSE) sequence with MSDE increases radiologistsf diagnostic performances in detecting brain metastases comparing to a conventional 3D gradient-echo sequence (MPRAGE). A jackknife free-response receiver operating characteristic (JAFROC) analysis showed that TSE with MSDE increases radiologistsf diagnostic performances compared to MPRAGE. The reading time was also significantly shortened by use of MSDE.