1Mirtech, Inc., Brockton, MA, United
States; 2Radiology, Brigham and Women's Hospital, Boston, MA,
United States; 3Dept. of Physics, University of Masachusetts at
Lowell, Lowell, MA, United States; 4Harvard School of Public
Health, Boston, MA, United States
A
theoretical model is presented to understand the XTC experiment with
hyperpolarized 129Xe for arbitrary flip angle. The model is flexible in that
different dissolved state diffusion models may be incorporated. The model
also illustrates fundamental differences between CSSR and XTC experiments. It
is clear that no single exchange time value dominates the time evolution of
the XTC signal. It is demonstrated that the XTC90 experiment (employing 90
flips instead of 180) should generate results similar to CSSR experiments.