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Abstract #1952

Diffusion Tensor Imaging in Patients with Alzheimers Disease and Mild Cognitive Impairment

Sidy Fall1, Souraya El Sankari2, Roger Bouzerar3, Bertille Perin4, Marc-Etienne Meyer5, Olivier Baledent3

1Imaging and Biophysics, University Hospital , Amiens, Picardie, France; 2Institute of Neuroscience, Cliniques Universitaires Saint-Luc, Brussels, Belgium; 3Imaging and Biophysics, University Hospital, Amiens, Picardie, France; 4Neurology , University Hospital, Amiens, Picardie, France; 5Nuclear Medicine, University Hospital, Amiens, Picardie, France


We used DTI to investigate inferior fronto-occipital fasciculus (IFO) alterations in patients with Alzheimers disease and Mild Cognitive Impairment (MCI). Within each group, we compared DTI parameters between the two hemispheres in IFO. We found no differences in DTI parameters between the two patients groups. Our results reveal that the longitudinal and radial diffusivities, fractional anisotropy and apparent diffusion coefficient were significantly higher on the right lobe than on the left lobe in AD group. While, Within the MCI group, only FA and radial diffusivity were higher on the right lobe than on the left lobe.