Jan Weis1, Lucian Covaciu2, Sten
Rubertsson2, Mats Allers3, Anders Lunderquist4,
Francisco Ortiz-Nieto1, Hkan Ahlstrm1
1Department of Radiology, University
Hospital, Uppsala, Sweden; 2Department of Surgical Sciences,
Anesthesiology and Intensive Care, University Hospital, Uppsala, Sweden; 3Department
of Clinical Sciencies, University Hospital, Lund, Sweden; 4Department
of Clinical Sciences, University Hospital, Lund, Sweden
Decrease
of the human brain temperature (1-2 oC in 15 minutes) was induced by
intranasal cooling. The purpose of this study was to verify the cooling
technique on the volunteers and to compare two methods for noninvasive
monitoring of the relative brain temperature: MRSI with high spatial and
reduced spectral resolution and PRF shift technique. Ability of the proposed
brain cooling technique to induce moderate hypothermia was confirmed. Good
agreement was found between relative temperatures measured by MRSI and PRF
method. Both temperature mapping techniques can be used for monitoring the
brain temperature changes during hypothermia.