Abstract #1750
Towards
an Optimal Distribution of B-Values for IVIM Imaging
Andreas Lemke1, Frederik Bernd Laun2,
Lothar Rudi Schad1, Bram Stieltjes3
1Deparmtent of Computer Assisted
Clinical Medicine, Heidelberg University, Mannheim, Germany; 2Department
of Medical Physics in Radiology, German Cancer Research Center, Heidelberg,
Germany; 3Deparmtent of Radiology, German Cancer Research Center,
Heidelberg, Germany
The
b-value distribution for IVIM imaging was optimized using Monte
Carlo simulations in order to minimize the uncertainty of the
biexponential fit. For three different parameter settings, illustrating the
IVIM parameters in brain, liver and kidney, the error of the calculated
optimal b-value distribution was compared with the error of previously
reported distributions. The error for this optimized distribution was
significantly lower for all parameter settings when compared with currently
used distributions. The results demonstrate that the presented choice of
b-values can substantially minimize the overall measurement error in IVIM and
may aid the choice of b-values in clinical experiments.
