Hilde Kjeldstad Berg1, Paal Erik Goa2,
Olav Haraldseth3, Henrik B W Larsson4
1HiST, Sor-Trondelag University
College, Trondheim, Norway; 2Department of Diagnostic Imaging, St
Olavs Hospital, Trondheim, Norway; 3Department of Circulation and
Medical Imaging, Norwegian University of Science and Technology (NTNU),
Trondheim, Norway; 4Functional Imaging Unit, Glostrup Hospital,
University of Copenhagen, Glostrup, Denmark
The
purpose of this study was to further develop and validate a new method for
quantitative cerebral perfusion measurements, using dynamic contrast enhanced
T1-weighted MR imaging. Healthy volunteers were examined in rest and during
visual stimulation. Visual stimulation resulted in a significant increase in
cerebral blood flow (CBF) in the occipital region, and the increase was in
accordance with literature values. In other areas of the brain, CBF remained
unchanged. Cerebral blood volume was also measured, but the increase observed
was not found to be significant.