Irvin Teh1,2, Xavier Golay1,3,
David Larkman2
1Lab of Molecular Imaging, Singapore
Bioimaging Consortium, Singapore, Singapore; 2Imaging Sciences
Department, Imperial College London, London, United Kingdom; 3Institute
of Neurology, University College London, London, United Kingdom
A
diffusion-weighted fast spin echo periodically rotated overlapping parallel
lines with enhanced reconstruction (DW-FSE-PROPELLER) sequence was combined
with a multiple axis Stejskal-Tanner diffusion weighting scheme that rotated
and alternated across blades. This reduced the number of DW acquisitions
needed to acquire the mean apparent diffusion coefficient from three to one,
halving the total acquisition time. This motion and distortion robust method
was tested in the in-vivo mouse brain and compared to previously proposed
rotating DW strategies.