Kilian Weiss1,
Nicola Martini2, Peter Boesiger1, Sebastian Kozerke1
1Institute for Biomedical Engineering,
University and ETH Zurich, Zurich, Switzerland; 2Interdepartmental
Research Center "E. Piaggio", University of Pisa, Pisa, Italy
Single-voxel
proton magnetic resonance spectroscopy has been shown to be a promising tool
for assessing creatine and myocardial triglycerides in humans. While spectral
information from a single volume is sufficient when alterations with global
effects on the heart are studied, a demand for higher and flexible spatial
resolution exists when probing local changes. To this end, implementation of
fast spectroscopic imaging of the heart is desired. The objective of the
current work was to implement and optimize navigator gated and cardiac
triggered Echo-Planar Spectroscopic Imaging (EPSI) for assessment of
triglyceride and creatine content in the myocardium in vivo.