Zungho
Zun1, Padmini Varadarajan2, Ramdas G. Pai2,
Eric C. Wong3, Krishna S. Nayak1
1Department of Electrical Engineering, University
of Southern California, Los Angeles, CA, United States; 2Division
of Cardiology, Loma Linda University Medical Center, Loma Linda, CA, United
States; 3Departments of Radiology and Psychiatry, University of
California, San Diego, La Jolla, CA, United States
Myocardial
arterial spin labeling (ASL) scans were performed at rest and during
adenosine infusion in eleven patients scheduled for CMR. Seven patients were
classified as normal based on having no visible perfusion defect on CMR
first-pass imaging. In these subjects,
there was a statistically significant increase in global myocardial blood
flow (MBF) measured during adenosine infusion (3.75 1.06 ml/g/min),
compared to at rest (1.09 0.53 ml/g/min).
This suggests that myocardial ASL may be capable of capturing
clinically relevant increases in MBF with vasodilation.