Duan Xu1,2, Natalie Charlton1,
Srivathsa Veeraraghavan1, Geoffrey T. Manley3, Pratik
Mukherjee1,2
1Dept of Radiology, UCSF, San
Francisco, CA, United States; 2UCSF/UC Berkeley Joint Graduate
Group in Bioengineering, San Francisco and Berkeley, CA, United States; 3Dept
of Neurosurgery, UCSF, San Francisco, CA, United States
Conventional
MR imaging does not accurately predict outcome in mild TBI, but MR diffusion
and proton spectroscopy has shown promise as potential biomarkers for injury
severity and long-term neurocognitive and functional outcome. In this study, we utilized 3D MRSI at 3T
with wide anatomic coverage to assess TBI in specific association,
commissural, and projection white matter tracts.