Richard Kijowski1, Catherine Debra Hines2,
Huanzhou Yu3, Scott Brian Reeder1,2
1Radiology, University of Wisconsin,
Madison, WI, United States; 2Medical Physics, University of
Wisconsin, Madison, WI, United States; 3GE Healthcare, Applied
Science Laboratory, Menlo Park, CA, United States
This
study was performed to demonstrate improvements in the quality of
fat-suppression for unspoiled GRASS imaging of the knee using multi-peak fat
spectral modeling and IDEAL fat-water separation. An IDEAL-GRASS sequence was
performed at 3.0T on the knees of 10 asymptomatic volunteers. The IDEAL-GRASS
images were reconstructed using a single-peak method and a multi-peak method
that more accurately models the NMR spectrum of fat. Multi-peak IDEAL-GRASS had significantly
greater (p<0.001) suppression of bone marrow signal and significantly
higher (p<0.001) CNR between cartilage and bone marrow than single-peak
IDEAL-GRASS.