Stefan
Hoffmann1, Paul Begovatz1, Armin Nagel1,
Reiner Umathum1, Michael Bock1
1Medical Physics in Radiology,
The
detection of oxygen-17 (17O) provides a method to assess metabolic tissue
information at ultra high fields. In this work direct 17O-MR imaging was
carried out in vivo on a 7 Tesla MR system with a custom built head coil.
Natural abundance imaging of the human head was performed and global
relaxation parameters were measured. An inhalation experiment with enriched
17O gas was carried out using an inhalation-triggered oxygen delivery system.
Imaging was performed prior to, during and after the inhalation showing an
increase of signal intensity during ventilation with enriched oxygen-17 gas.