Ken-Pin Hwang1,2, Zhenghui Zhang3,
Brandy J. Reed4, Michelle L. Underwood4, Roger Jason
Stafford4, Peggy T. Tinkey5, David C. Alsop6,7,
Rajesh Uthamanthil5
1Applied Science Laboratory, General
Electric Healthcare, Houston, TX, United States; 2Department of
Imaging Physics, UT MD Anderson Cancer Center, Houston, TX, United States; 3GE
Healthcare, Waueksha, WI, United States; 4Department of Imaging
Physics, University of Texas MD Anderson Cancer Center, Houston, TX, United
States; 5Department of Veterinary Medicine and Surgery, University
of Texas MD Anderson Cancer Center, Houston, TX, United States; 6Department
of Radiology, Beth Israel Deaconess Medical Center, Boston, MA, United
States; 7Department of Radiology, Harvard Medical School, Boston,
MA, United States
The
use of a modified phase contrast gradient echo sequence has been shown to be
a robust technique for MR elastography of the liver. However, each phase encoded view requires
long motion encoding gradients that extended the echo time, making the
sequence sensitive to susceptibility and lengthening overall acquisition
time. In this work we combine a motion
encoding preparation sequence with an SSFSE sequence originally designed for
diffusion weighted imaging. Phase
information from a single set of motion encoding gradients is preserved for
each echo in the echo train, thus accelerating acquisition in a spin echo based
sequence.