Curtis L. Johnson1, Danchin Chen1,
Harish Sharma2, Bradley P. Sutton, 2,3, William C.
Olivero, 2,4, John G. Georgiadis1,2
1Mechanical Science and Engineering
Department, University of Illinois at Urbana-Champaign, Urbana, IL, United
States; 2Beckman Institute for Advanced Science and Technology,
University of Illinois at Urbana-Champaign, Urbana, IL, United States; 3Bioengineering
Department, University of Illinois at Urbana-Champaign, Urbana, IL, United
States; 4Department of Neurosurgery, University of Illinois at
Urbana-Champaign, Urbana, IL, United States
The
effects of encoding displacement at a frequency other than the driving
frequency with Magnetic Resonance Elastography (MRE) were investigated. Off-frequency responses can occur due to
possible nonlinearities in the overall dynamic system being actuated. Results demonstrated that undesired off-frequency
encoding could result in errors in mean estimated stiffness of tissue, as
well as local fluctuations in estimated stiffness, which will have
implications for MRE with nonlinear dynamic systems.