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Abstract #2127

Small-Voxel High Spatial and Spectral Resolution (HiSS) MRI of Human Breast: A Pilot Study

Milica Medved1, Gillian M. Newstead1, Hiroyuki Abe1, Abbie M. Wood1, Akiko Shimauchi1, Olufunmilayo I. Olopade2, Stefan Fischer3, Sri Swaminathan3, Marko Ivancevic3, Gregory S. Karczmar1

1Radiology, University of Chicago, Chicago, IL, USA; 2Medicine, University of Chicago, Chicago, IL, USA; 3Philips Medical Systems, Cleveland, OH, USA


Small-voxel HiSS is a novel approach to MRI of the breast that is likely to increase its diagnostic utility. Twelve women were scanned using an echo-planar spectroscopic imaging-based sequence, in 1 mm thick slices with either 0.50 mm or 0.75 mm in-plane resolution, and with spectral resolution of 5 or 18 Hz, respectively. Images proportional to water resonance peak height were constructed. Even in small voxel sizes, adequate SNR, high dynamic range, uniform and complete fat suppression, and excellent contrast and margin delineation of lesion and parenchyma were achieved.