Abstract #2126

Quantitative MRI Technique for Mapping the T1/T2 Ratios of Benign and Malignant Breast Lesions

M. A. Malikova¹, Jaroslaw Nicholas Tkacz², Adam Yaakil², Priscilla Slanetz³, Hernan Jara²

¹Surgery, Boston University Medical Center, Boston, MA, USA; ²Radiology, Boston University Medical Center, Boston, MA, USA; ³Radiology, Beth Israel Medical Center, Boston, MA, USA

We have developed a quantitative MRI technique for mapping the longitudinal-to-transverse relaxation times ratio (T1/T2) of benign and malignant breast lesions. This technique gives reliable quantitative results and produces high image quality on T1, T2, and T1/T2 maps, as tested on 20 female subjects with known or suspected lesions proven by biopsy and pathologic correlation. In our small series, there is a statistically significant difference in the T1/T2 ratios of benign and malignant breast lesions using this technique.