Abstract #2077

Improved Contrast Enhancement of Experimentally Induced Rat Hepatocellular Carcinoma Using New Blood Pool Contrast Agent Dendrimers DTPA-D1Glc(OH)

Yasuo Takehara¹, Takashi Aoki², Mitsuji Yamashita², Michio Fujie³, Katsuaki Muramatsu³, Harumi Sakahara³, Norihiro Sadato⁴, Hiroyasu Takeda³

¹Radiology, Hamamatsu University Hospital, Hamamatsu, Shizuoka, Japan; ²Shizuoka University Graduate School of Technology; ³Hamamatsu University School of Medicine; ⁴National Institute for Physiological Science

Newly developed blood pool agent can provide improved and sustained contrast enhancement of experimentally induced rat hypervascular hepatocellular carcinoma with lower dosage of 1/8 of Gd-DTPA at molecular basis.