Abstract #0925

Single Cell Tracking of Neural Progenitors Labeled in Vivo with Micron Sized Particles of Iron Oxide (MPIO) Into Specific Layers of the Olfactory Bulb

James P. Sumner¹, Stephen Dodd¹, Elizabeth Wayne^1,2, Der-Yow Chen¹, Yun Chen^1,3, Dragan Maric^1,4, Alan P. Koretsky¹

¹National Institutes of Health, Bethesda, MD, USA; ²University of Pennsylvania, Philadelphia, PA, USA; ³National Institute of Standards and Technology; ⁴NINDS FACS Facility, Bethesda, MD, USA

In this work, MRI was used to track neural progenitors (NPCs) into the olfactory bulb with 50 μm isotropic resolution. At this resolution and with the aid of manganese, NPCs were identified and quantified in each layer of the bulb. Olfactory bulbs from naive and animals exposed to amyl acetate were compared.