Chunmei Li1, Guodong Song1, Yuhui Chen1, Xuna Zhao2, Jinyuan Zhou2, and Min Chen1
1Beijing Hospital, Beijing, China, People's Republic of, 2Johns Hopkins University, Baltimore, MD, United States
This study is to evaluate the
longitudinal Amide Proton Transfer-weighted (APTw) signal changes in patients
with stroke after treatment. APT weighted images of stroke patients was
acquired, including non-treatment and post treatment.
91.7% patients (22/24) showed gradual increased APT values with the
extension of time, accompanied with the clinical symptoms improvement. The
other 2 patients (8.3%) showed further decreased APT values in the second scan
(the first scan after treatment), accompanied with the clinical symptoms
aggravation. The increase of APT weighted signal may indicate the improvement
of clinical symptoms while the decrease may indicate the aggravating of
clinical symptoms.