Yi-Shin Chang1, Mathilde Gratiot1, Julia Owen1, Anne Brandes-Aitken1, Shivani Desai1, Susanna Hill1, Anne Arnett1, Julia Harris1, Elysa Marco1, and Pratik Mukherjee1
Sensory
processing disorders (SPD) affect 5-16% of school-aged children, and can cause
downstream deficits of intellectual and social development. In this study, we
use diffusion tensor imaging to study a cohort of 41 children with SPD and 41
typically developing children ages 8-12. We confirm and generalize results from
our prior pilot study indicating disrupted posterior white matter in SPD, and
further demonstrate a relationship between direct measurements of tactile and
non-linguistic auditory function and white matter microstructure -- not just
in SPD, but also in typically developing children.