Liangjie Lin1, Yanqin Lin1, Zhiliang Wei1, and Zhong Chen1
Magnetic resonance spectroscopy (MRS) is a
powerful noninvasive tool in diagnoses, progressive monitoring, and studies of
disease states of humans and animals. In this study, we present a MRS pulse
sequence for localized one-dimensional in-phase proton MRS. The proposed pulse
sequence can be utilized to reduce undesired broad resonances with short T2s
and increasing signal intensity of J
coupling metabolites. Moreover, it provides an approach of direct measurement
of non-overlapping J coupling peaks
at achievable arbitrary TEs and of their transverse relaxation times (T2).
