Abstract #3747

Dynamic Reconfiguration of Intrinsic Functional Connectivity: A Probabilistic Framework

Dazhi Yin¹, Kristina Zeljic¹, Zhiwei Wang¹, Qian Lv¹, and Zheng Wang¹

¹Institute of Neuroscience, Chinese Academy of Sciences, Shanghai, China, People's Republic of

Neural basis enabling flexible behavior remains largely unknown. Based on the spatiotemporal dynamics of intrinsic functional connectivity, we proposed a probabilistic modeling framework to quantify the functional flexibility and integration of different brain regions. We then applied this framework to investigate the functional representation of hand preference. Our findings revealed higher functional flexibility and integration for the preferred hand that controls cognitive-motor requirements for skilled movements.

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