Pulmonary Perfusion using pseudo-Continuous Arterial Spin Labeling
Joshua S. Greer1,2, Xinzeng Wang2, Ivan Pedrosa2,3, and Ananth J. Madhuranthakam2,3
1Bioengineering, University of Texas at Dallas, Richardson, TX, United States, 2Radiology, UT Southwestern Medical Center, Dallas, TX, United States, 3Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States
Cardiac triggering is regularly used in arterial spin
labeled (ASL) pulmonary perfusion imaging to minimize pulsatile flow effects. A
cardiac-triggered pseudo-continuous ASL (pCASL) sequence was previously implemented
to improve the SNR of lung perfusion, but was found to be sensitive to
variations in heart rate due to the prolonged TR, causing the data acquisition
to occasionally occur during systole. The purpose of this study was to investigate
methods to reduce this cardiac cycle sensitivity in pulmonary perfusion images
using pCASL, including cardiac triggering the acquisition and alternative
readouts such as a projection acquisition.
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