Michael Dacko1, Benjamin Knowles1, Patrick Hucker1, Maxim Zaitsev1, and Thomas Lange1
Diffusion-weighted
spectroscopy of the brain is a highly motion-sensitive MR method as a
consequence of the large voxel size and low metabolite diffusion
coefficients. In this work, we correct for voxel displacement during
DWS experiments with prospective motion correction and investigate
the signal attenuation due to rotation-induced intra-voxel
dephasing. Phantom experiments with 'synthetic' rotations
confirmed the theoretically predicted signal attenuation. High
correlation between rotational motion and attenuation of the residual
water peak was observed in vivo. Retrospective rejection criteria
based on the recorded motion tracking data and on the residual water
peak amplitude are compared.
