Åsmund Kjørstad1, Fabian Temme1, Jens Fiehler1, and Jan Sedlacik1
Targeted temperature
management is a treatment that seeks to reduce and control the body
temperature. We demonstrate a novel localized cooling technique using high flow
cold air applied nasally and orally to the airways by monitoring the brain
temperature using gradient echo phase imaging at 3T. 2 healthy volunteers were
investigated, with one subject being scanned twice and the other once. A
significant temperature reduction (p<0.05) was seen in the inferior frontal
lobe in all three experiments with an average cooling effect of -0.33°C. This
demonstrates the feasibility of our proposed high flow cold air system.