Abstract #1487

A Perfusion Phantom for Arterial Spin Labeled MRI

Hyo Min Lee^1,2, Marta Vidorreta^3,4, Yulin Vince Chang³, and John Alan Detre^3,4

¹Bioengineering, University of Pennsylvania, Philadelphia, PA, United States, ²Institute for Biomedical Engineering, University and ETH Zürich, Zürich, Switzerland, ³Radiology, University of Pennsylvania, Philadelphia, PA, United States, ⁴Neurology, University of Pennsylvania, Philadelphia, PA, United States

ASL MRI is an appealing biomarker for clinical research and management, but ASL MRI sequences are difficult to calibrate because a reliable phantom for simulating tissue-specific perfusion has yet to be developed. In this work, we describe a prototype perfusion phantom based on 3D printed vessels and mock parenchyma that may allow reliable, ex-vivo assessments of ASL sequences.

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