Whole brain volumetric perfusion imaging with high spatial resolution using simultaneous multi-slab (SMSB) 3D GRASE pCASL
Yi Wang1, Xingfeng Shao1, Steen Moeller2, and Danny JJ Wang1
1Neurology, UCLA, Los Angeles, CA, United States, 2Center of Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States
The temporal SNR of simultaneous multi-slice (SMS) 2D EPI ASL has been shown to be
inferior to that of 3D background suppressed GRASE. In this work, we present a
novel simultaneous multi-slab (SMSB) 3D GRASE sequence for volumetric pCASL
imaging with high spatial resolution. The image quality of SMSB-GRASE was
evaluated and compared to a standard 3D GRASE pCASL sequence. Preliminary results
demonstrated the feasibility for whole-brain volumetric perfusion imaging at a
high spatial resolution, although the drop in RF slice profiles in the
overlapped boundary slices still needs to be addressed in future work.
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