Abstract #1171

The Neural Basis of Visual Field Asymmetry in Human Visual System by Functional MRI

Caitlin O'Connell¹, Leon Ho^2,3, Matthew Murphy², Yolandi van der Merwe^1,2, Ian Conner^1,2, Gadi Wollstein^1,2, Joel Schuman^1,2, Rakie Cham¹, and Kevin Chan^1,2

¹Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States, ²UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center, Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, United States, ³Department of Electrical and Electronic Engineering, The University of Hong Kong, Pokfulam, Hong Kong

Human visual performance has been observed to exhibit superiority in the lower visual field and horizontal meridian compared to the upper visual field and vertical meridian, respectively, in response to many classes of stimuli, but the underlying neural mechanisms remain unclear. This study determines if processing of visual information is dependent on the location of stimuli in the visual field using functional MRI. The results show stronger brain responses and larger activation volumes upon flickering visual stimulation to the lower hemifield compared to upper hemifield, while only the activation size differed between visual presentations to the horizontal and vertical meridians.

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