Precise staging of preoperative 3.0-T MR imaging for esophageal carcinoma by using ex vivo MR imaging-matched pathologic findings as the reference standard
Yi Wei1,2, Shao-Cheng Zhu1,2, Sen Wu1,2, Da-Peng Shi1,2, and Dan-Dan Zheng3
1Radiology, Zhengzhou University People's Hospital, Zhengzhou, China, People's Republic of, 2Henan Provincial People's Hospital, Zhengzhou, China, People's Republic of, 3GE Healthcare,MR Research China, Beijing, China, People's Republic of
Magnetic resonance imaging (MRI) was reported to evaluate the esophageal layers invasion in vitro and demonstrated that high-resolution T2-weighted imaging can clearly depict 8 layers of esophagus. However, former studies were mostly carried on ultra-high-field scanner ex vivo, which can not satisfy the need of preoperative staging and provide essential information for clinic. In this study, an in vivo experiment was conducted on 3.0T clinical scanner to prospectively establish the MRI signal characteristics of the normal esophageal wall and to assess the diagnostic accuracy of high-resolution MR imaging for depicting the depth of esophageal wall invasion by corresponding to ex vivo MR imaging-matched certain histopathological slice.
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