Casey Anderson1, Andrew Nencka2, Tugan Muftuler3, Kathleen Schmainda2, and Kevin Koch2
1Biophysics, Medical College of Wisconsin, Milwaukee, WI, United States, 2Radiology, Medical College of Wisconsin, Milwaukee, WI, United States, 3Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, United States
Quantitative
susceptibility maps are routinely compromised by streaking artifacts.
Here, we present a technique called volume-parcellated quantitative
susceptibility mapping (VP-QSM), which performs independent susceptibility
inversion on multiple reduced field-of-view parcels over the entire tissue
field map. These parcels are combined to
form a composite susceptibility map. In
this algorithm, streaking artifacts are confined to individual parcels,
improving the quality of the susceptibility map without a dependence on the
underlying QSM inversion algorithm. In this study, VP-QSM is demonstrated on a 7T
human volunteer, as well as on 30 subjects participating in sports concussion
and brain cancer neuroimaging research protocols.
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