Abstract #0880

Impact of MR-based PET motion correction on the quantification of myocardial blood flow: an in-vivo simultaneous MR/PET study

Yoann Petibon¹, Behzad Ebrahimi¹, Timothy G Reese^1,2, Nicolas Guehl¹, Marc D Normandin¹, Nathaniel M Alpert¹, Georges El Fakhri¹, and Jinsong Ouyang¹

¹Center for Advanced Medical Imaging Sciences, Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States, ²Athinoula A. Martinos Center, Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States

Dynamic PET imaging enables absolute quantification of myocardial blood flow (MBF). However, motion of the heart during imaging deteriorates the accuracy of PET MBF measurements. Simultaneous MR/PET makes it possible to compensate PET images for motion by incorporating MR-based motion information inside the PET reconstruction process. In this study, we propose and assess the impact of a tagged-MRI based PET motion-correction technique for improved PET MBF quantification using an in-vivo simultaneous MR/PET study.

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