Abstract #0879

Respiratory Resolved Attenuation Correction Maps for Motion Compensated PET-MR using Dixon-GRPE

Christoph Kolbitsch^1,2, Radhouene Neji³, Matthias Fenchel⁴, and Tobias Schaeffter^1,2

¹Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom, ²Physikalisch-Technische Bundesanstalt (PTB), Braunschweig and Berlin, Germany, ³MR Research Collaborations, Siemens Healthcare, Frimley, United Kingdom, ⁴MR Oncology Application Development, Siemens Healthcare, Erlangen, Germany

Quantitative PET requires accurate attenuation correction (AC) information. For simultaneous PET-MR acquisitions in the thorax or abdomen these MRAC images are obtained in a single breathhold which can lead to misregistration errors between breathhold MRAC and free-breathing PET data. Here we present a method which obtains accurate AC information (Dice coefficient higher than 0.85) during free-breathing and yields additional respiratory motion fields which can be utilised in motion-compensated MR and PET reconstructions. The proposed Dixon-GRPE method led to improvements of up to 50% in sharpness (FWHM) and a 33% improvement in the quantification of the specific uptake value (SUV).

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