Acceleration of 3D UTE Imaging to Quantify Temperature-Dependent T1 Changes in Cortical Bone
Misung Han1, Wenwen Jiang2, Roland Krug1, Peder Larson1,2, and Viola Rieke1
1Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States, 2Joint Graduate Program in Bioengineering, University of California, San Francisco/Berkeley, San Francisco, CA, United States
High-intensity
focused ultrasound (HIFU) is a promising, noninvasive technique to ablate bone
tumors and palliate painful bone metastases. During HIFU treatment, temperature
mapping is desirable for proper heat deposition to targeted bone regions. Even
though conventional PRF-based thermometry cannot be applied for cortical bone
due to its short T2 relaxation time, it was demonstrated using 3D UTE imaging can
be used to measure T1 changes due to heating. In this work, we accelerated 3D UTE
imaging by combining parallel imaging and compressed sensing and compared calculated
T1 changes due to heating with those from fully sampled data.
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