Abstract #0600

Serial Quantification of Brain Oxygenation using Streamlined-qBOLD in Acute Stroke Patients

Alan J Stone¹, George WJ Harston², Davide Carone², Mmua Ngwako², Radim Licenik², James Kennedy ², and Nicholas P Blockley¹

¹FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom, ²Acute Stroke Programme, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom

Streamlined-qBOLD is applied to an exploratory cohort of acute stroke patients in a serial imaging study to map brain oxygen metabolism. Quantitative brain oxygenation parameters are demonstrated to vary between regions with different tissue outcomes and this imaging approach is shown to have the potential to refine the identification of the ischemic penumbra.

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