High Quality Preclinical 4D-Flow Phase Contrast Imaging
Moritz Braig1, Jochen Leupold1, Ko Cheng-Wen2, Marius Menza1, Juergen Hennig1, Jan Korvink3, and Dominik von Elverfeldt1
1University Medical Center Freiburg, Freiburg, Germany, 2Dept. Computer Science and Engineering, National Sun Yat-sen University, Kaohsiung, Taiwan, 3Institute of Microstructure Technology, Karlsruhe Institute of Technology, Karlsruhe, Germany
So far
preclinical 4D-Flow MRI has not been able to deliver an analysis of complex flow due to low resolution. The presented framework and improvements allow
high quality data acquisitions with a reduced measurement time and the possibility
to visualize regional flow abnormalities. An automatic magnitude
segmentation in every timeframe combines anatomic information with the
underlying blood flow showing even small vessels. It will draw new conclusions
in mouse models of cardiovascular diseases as a valuable tool for preclinical
researchers.
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