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Abstract #4776

Preliminary results of evaluating feasibility of T1 SPACE to detect intracranial atherosclerosis

Woojin Lee 1 , Bo-mi Gil 1 , Jinhee Jang 1 , Bom-yi Kim 1 , In Seong Kim 2 , Hyun Seok Choi 1 , So Lyung Jung 1 , Kook-Jin Ahn 1 , and Bum-soo Kim 1

1 Department of Radiology, Seoul St. Mary's Hospital,College of Medicine, Catholic University of Korea, Seocho-gu, Seoul, Korea, 2 Siemens Healthcare, Korea, Seoul, Korea

As MR angiography cannot demonstrate vessel wall, vessel wall imaging is important to detect vulnerable atherosclerotic plaque. The goal of this study was to evaluate feasibility of T1 SPACE to detect intracranial atherosclerosis in nonsymptomatic patient. Twenty nonsymptomatic patients underwent both TOF and T1 SPACE using 3.0 Tesla MR system were enrolled.TOF-source was considered as a reference standard for lumen of intracranial arteries. We measured luminal area of basilar artery and both cavernous internal carotid arteries on T1 SPACE and TOF source and vessel wall thickness by subtracting luminal diameter on TOF-source from outer diameter on T1-SPACE.Vessel areas measured from TOF-source and T1 SPACE showed significant linear correlation.However,there was no correlation between atherosclerotic risk factors and vessel wall thickness.

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