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Abstract #4727

Volumetric changes of subcortical nuclei in Mild Cognitive Impairment Converter: A longitudinal MRI study

Xiaojing Long 1 , Weiqi Liao 1 , Chunxiang Jiang 1 , Dai Shan 1 , Yanjun Diao 1 , and Lijuan Zhang* 1

1 Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China

Previous studies have demonstrated volume shrinkage of subcortical nuclei in the brain of mild cognitive impairment (MCI). However, the evolution of the volumetric changes remains to be defined. In this study, we aimed to investigate the atrophy trajectory of subcortical structures from longitudinal data.

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