Abstract #4726
Brain Perfusion and Glucose Metabolism by Simultaneous FDG-PET/MR-ASL in Patients with Cognitive Disorders: Initial Experience.
Marco Aiello
1
, Carlo Cavaliere
1
,
Ilaria Boscolo Galeazzo
2
, Elena Salvatore
3
,
Francesca B. Pizzini
4
, Alberto Beltramello
4
,
and Emanuele Nicolai
1
1
IRCCS fondazione SDN, Naples, Italy,
2
University
of Verona, Italy,
3
Universit
di Napoli Federico II, Italy,
4
General
Hospital, Verona, Italy
Simultaneous acquisition of brain metabolism and
perfusion by hybrid FDG- PET/MR arterial spin labeling
(ASL) may better characterise physio-pathological
processes underpinning cognitive disorders. Many
technical issues should be considered. While collecting
patients group data, here we present 4 typical
case-reports. We found a good agreement between blood
perfusion and glucose metabolism in MCI and AD. As for
as vascular dementia patient, a mismatch between
perfusion and metabolism raised up, showing a decreased
frontal perfusion in absence of significant metabolism
reduction in these areas. These preliminary data show
good feasibility in terms of image quality and patient
endurance.
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