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Abstract #4709

Widespread brain changes in patients with advanced glaucoma

Antonio Giorgio 1 , Paolo Frezzotti 2 , Ilaria Motolese 2 , Eduardo Motolese 2 , Antonio Federico 1 , and Nicola De Stefano 1

1 Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Siena, Italy, 2 Department of Surgery, Ophthalmology Unit, University of Siena, Siena, Siena, Italy

By using a multimodal MRI approach, this study demonstrates in patients with advanced primary open angle glaucoma (POAG) the presence of structural and functional changes that go well beyond the visual system, thus providing evidence that POAG can be considered a vision disorder belonging to the group of neurodegenerative conditions and, as such, spreading throughout the brain

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