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Abstract #4558

Effective in-plane distortion correction for 3DGRASE ASL acquisitions

Enrico De Vita 1,2 , Evelyne Balteau 3 , Xavier Golay 2 , and David L Thomas 2

1 Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, London, United Kingdom, 2 Academic Neuroradiological Unit, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, London, United Kingdom, 3 Cyclotron Research Centre, University of Lige, Liege, Belgium

3DGRASE is an extremely efficient acquisition strategy for ASL. Blurring in slice/partition direction, related to excessively long echo trains, is an issue in single-shot acquisitions. This blurring can be decreased with multi-shot acquisitions. In-plane geometric distortions related to the GE-EPI readout caused by magnetic susceptibility variations across the brain are still a nuisance. We test the effectiveness of a susceptibility distortion correction based on B0-field maps, similarly to that routinely used for fMRI. An M0 acquisition repeated by inverting the in-plane phase-encoding direction can be used to generate a usable B0 map in alternative to the conventional double-echo GE-2DFT acquisition.

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